How are Cytoplasmic Inclusion Bodies Identified in Histology?
Cytoplasmic inclusion bodies can be identified using a variety of staining techniques and microscopy methods:
Light Microscopy: Hematoxylin and eosin (H&E) staining is commonly used to identify general cellular structures, including some inclusion bodies. Special Stains: Periodic acid-Schiff (PAS) stain is often used to identify glycogen granules, while Oil Red O or Sudan Black stains are used for lipid droplets. Electron Microscopy: Provides detailed images of inclusion bodies, revealing their sub-structural characteristics and composition. Immunohistochemistry: Uses antibodies to detect specific proteins within inclusion bodies, aiding in their identification and study.
