Aggregates can form through various mechanisms depending on the context:
Cell-Cell Adhesion: Cells often aggregate by adhering to each other using surface molecules known as cell adhesion molecules (CAMs). Protein Misfolding: Proteins can aggregate when they misfold, exposing hydrophobic regions that lead to clumping. Lipid Accumulation: Lipids may aggregate when there is an imbalance in lipid metabolism, leading to storage in tissues. Immune Response: Immune cells may aggregate in response to infection or injury, forming structures like granulomas.
