Can Histology Differentiate Between Different Types of Pulmonary Fibrosis?
Yes, histology can differentiate between various types of pulmonary fibrosis. For instance, Idiopathic Pulmonary Fibrosis (IPF) shows a characteristic pattern of usual interstitial pneumonia (UIP), with patchy fibrosis, fibroblastic foci, and honeycombing. In contrast, Non-Specific Interstitial Pneumonia (NSIP) exhibits uniform interstitial inflammation and fibrosis without the architectural distortion seen in UIP.