Receptor Tyrosine Kinase (rtk) Pathway - Histology

Relevant Publications

DCBLD2 deletion increases hyperglycemia and induces vascular remodeling by inhibiting insulin receptor recycling in endothelial cells.

Issue Release: 2024

Genomic characterization reveals distinct mutational landscapes and therapeutic implications between different molecular subtypes of triple-negative breast cancer.

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The IL-17 pathway intertwines with neurotrophin and TLR/IL-1R pathways since its domain shuffling origin.

Issue Release: 2024

Clinical relevance of somatic mutations in Chinese lung adenocarcinoma and their prognostic implications for survival.

Issue Release: 2024

GRB2: A dynamic adaptor protein orchestrating cellular signaling in health and disease.

Issue Release: 2024

RAS/Mitogen-Activated Protein Kinase Signaling Pathway in Testicular Germ Cell Tumors.

Issue Release: 2024

Characterization of gastric cancer-stimulated signaling pathways and function of CTGF in cancer-associated fibroblasts.

Issue Release: 2024

SUMOylation Fine-Tunes Endothelial HEY1 in the Regulation of Angiogenesis.

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Inhibition of DDR1 promotes ferroptosis and overcomes gefitinib resistance in non-small cell lung cancer.

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Effects of imidazole derivatives on cellular proliferation and apoptosis in myeloid leukemia.

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Targeting epidermal growth factor receptor and its downstream signaling pathways by natural products: A mechanistic insight.

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Negative prognostic impact of Co-mutations in TGFβ and TP53 pathways in surgically resected rectal tumors following neoadjuvant chemoradiotherapy.

Issue Release: 2024

RAF and MEK Inhibitors in Non-Small Cell Lung Cancer.

Issue Release: 2024

Recent advances in c-Met-based dual inhibitors in the treatment of cancers.

Issue Release: 2024

Combined treatment with cetuximab and STA9090 has synergistic anticancer effects on human non-small cell lung cancer.

Issue Release: 2024

Single-arm study of camrelizumab plus apatinib for patients with advanced mucosal melanoma.

Issue Release: 2024

Oxidative protein damage negatively affects protein-protein interaction: The case of KRAS-cRAF.

Issue Release: 2024

MEK inhibitors lead to PDGFR pathway upregulation and sensitize tumors to RAF dimer inhibitors in NF1-deficient malignant peripheral nerve sheath tumor (MPNST).

Issue Release: 2024

The oncogenic ADAMTS1-VCAN-EGFR cyclic axis drives anoikis resistance and invasion in renal cell carcinoma.

Issue Release: 2024

SPROUTY2, a Negative Feedback Regulator of Receptor Tyrosine Kinase Signaling, Associated with Neurodevelopmental Disorders: Current Knowledge and Future Perspectives.

Issue Release: 2024

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