In histology, the primary purpose of mutation analysis is to understand the genetic alterations that contribute to disease pathology. This can help in:
1. Diagnosis: Identifying specific mutations can aid in the accurate diagnosis of diseases. For instance, mutations in the _BRCA1_ and _BRCA2_ genes are linked to a higher risk of breast cancer. 2. Prognosis: Certain mutations can provide information about the likely course of a disease. For example, mutations in the _TP53_ gene are often associated with a poorer prognosis in various cancers. 3. Therapeutic Targets: Mutation analysis can help identify potential targets for therapy. Drugs can be designed to specifically target mutated proteins, offering personalized treatment options.
