What is the Importance of Gene Expression in Tissue Function?
Gene expression must be tightly regulated to maintain tissue function. Abnormal gene expression can lead to diseases such as cancer. For example, the overexpression of oncogenes or the underexpression of tumor suppressor genes can result in uncontrolled cell proliferation. Histological techniques such as immunohistochemistry and in situ hybridization are used to study gene expression patterns in tissues, providing insights into normal physiology and disease states.