Peyer's Patches play several vital roles in the immune system:
Antigen Sampling: M cells in the FAE capture and transport antigens from the gut lumen to immune cells within the Peyer's Patches. Immune Response: B and T lymphocytes within the Peyer's Patches respond to antigens by generating specific immune responses, including the production of immunoglobulin A (IgA). Immune Tolerance: Peyer's Patches help in maintaining tolerance to harmless antigens such as food proteins and commensal bacteria, preventing unnecessary immune reactions.
