Mutations or deficiencies in DMP1 can lead to several pathological conditions:
Hypophosphatemic Rickets: A condition characterized by low phosphate levels, leading to weak and soft bones. Dentinogenesis Imperfecta: A disorder resulting in discolored, weak, and brittle teeth. Osteomalacia: Softening of the bones due to defective bone mineralization.
These conditions highlight the importance of DMP1 in maintaining the structural integrity of mineralized tissues.
