What are the Histological Features of Neurotoxicity?
Histological features of neurotoxicity can vary depending on the type and extent of damage. Key features often include:
Neuronal death: Loss of neurons in specific brain regions. Gliosis: Proliferation of glial cells such as astrocytes and microglia in response to injury. Demyelination: Loss of the myelin sheath that insulates nerve fibers. Axonal degeneration: Breakdown of the axon, which impairs neuronal communication. Synaptic loss: Reduction in the number of synapses, affecting neural connectivity.