What Are Key Histological Features Indicative of High Aggressiveness?
1. Poor Differentiation: Tumors with poorly differentiated cells, which look very different from normal cells, are often more aggressive. 2. High Mitotic Index: A high number of cells undergoing mitosis indicates rapid cell division and hence, higher aggressiveness. 3. Necrosis: The presence of dead cells within the tumor often suggests a high growth rate, outpacing the blood supply. 4. Invasion and Metastasis: Evidence of tumor cells infiltrating surrounding tissues or blood vessels indicates a higher potential for metastasis.
