Two Pore Domain Potassium Channels - Histology

Relevant Publications

A leak K channel TWK-40 sustains the rhythmic motor program.

Issue Release: 2024

Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation.

Issue Release: 2024

TASK-3, two-pore potassium channels, contribute to circadian rhythms in the electrical properties of the suprachiasmatic nucleus and play a role in driving stable behavioural photic entrainment.

Issue Release: 2024

Sortilin-Mediated Inhibition of TREK1/2 Channels in Primary Sensory Neurons Promotes Prediabetic Neuropathic Pain.

Issue Release: 2024

Electronic Polarization Leads to a Drier Dewetted State for Hydrophobic Gating in the Big Potassium Channel.

Issue Release: 2024

Effect of two activators on the gating of a K channel.

Issue Release: 2024

Long-term follow-up of TREK-1 KO mice reveals the development of bladder hypertrophy and impaired bladder smooth muscle contractility with age.

Issue Release: 2024

Structure of an open K channel reveals tandem PIP binding sites mediating the Kir6.2 and SUR1 regulatory interface.

Issue Release: 2024

Novel insights into the modulation of the voltage-gated potassium channel K1.3 activation gating by membrane ceramides.

Issue Release: 2024

Osmotically Sensitive TREK Channels in Rat Articular Chondrocytes: Expression and Functional Role.

Issue Release: 2024

The Variety of Mechanosensitive Ion Channels in Retinal Neurons.

Issue Release: 2024

The Inhibition of TREK-1 K Channels via Multiple Compounds Contained in the Six Kamikihito Components, Potentially Stimulating Oxytocin Neuron Pathways.

Issue Release: 2024

The TREK-1 potassium channel is a potential pharmacological target for vasorelaxation in pulmonary hypertension.

Issue Release: 2024

Up-regulated expression of two-pore domain K channels, KCNK1 and KCNK2, is involved in the proliferation and migration of pulmonary arterial smooth muscle cells in pulmonary arterial hypertension.

Issue Release: 2024

C-type inactivation and proton modulation mechanisms of the TASK3 channel.

Issue Release: 2024

Overexpressed KCNK1 regulates potassium channels affecting molecular mechanisms and biological pathways in bladder cancer.

Issue Release: 2024

Atomistic mechanism of coupling between cytosolic sensor domain and selectivity filter in TREK K2P channels.

Issue Release: 2024

Evolution of two-pore domain potassium channels and their gene expression in zebrafish embryos.

Issue Release: 2024

The complex regulation of Slo1 potassium channels from a structural perspective.

Issue Release: 2024

Potassium channel TASK-5 forms functional heterodimers with TASK-1 and TASK-3 to break its silence.

Issue Release: 2024

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