Protein Misfolding Cyclic Amplification (pmca) - Histology

Relevant Publications

Ligand Profiling as a Diagnostic Tool to Differentiate Patient-Derived α-Synuclein Polymorphs.

Issue Release: 2024

Longitudinal detection of prion infection in preclinical sheep blood samples compared using 3 assays.

Issue Release: 2024

Pathological α-synuclein detected by real-time quaking-induced conversion in synucleinopathies.

Issue Release: 2024

PMCA to demonstrate prions inactivation method efficacy on reusable medical devices: a relevant alternative to animal bioassays.

Issue Release: 2024

Enhanced detection of chronic wasting disease in muscle tissue harvested from infected white-tailed deer employing combined prion amplification assays.

Issue Release: 2024

Adaptation of the protein misfolding cyclic amplification (PMCA) technique for the screening of anti-prion compounds.

Issue Release: 2024

Seeding Aggregation Assays in Lewy Bodies Disorders: A Narrative State-of-the-Art Review.

Issue Release: 2024

α-Synuclein: A Promising Biomarker for Parkinson\'s Disease and Related Disorders.

Issue Release: 2024

Nasal bots carry relevant titers of CWD prions in naturally infected white-tailed deer.

Issue Release: 2024

Transmission of Norwegian reindeer CWD to sheep by intracerebral inoculation results in an unusual phenotype and prion distribution.

Issue Release: 2024

Screening of Anti-Prion Compounds Using the Protein Misfolding Cyclic Amplification Technology.

Issue Release: 2024

Minor prion substrains overcome transmission barriers.

Issue Release: 2024

Development of a methodology for large-scale production of prions for biological and structural studies.

Issue Release: 2023

Fluid and Biopsy Based Biomarkers in Parkinson\'s Disease.

Issue Release: 2023

Recombinant ovine prion protein can be mutated at position 136 to improve its efficacy as an inhibitor of prion propagation.

Issue Release: 2023

Seed amplification assay for the detection of pathologic alpha-synuclein aggregates in cerebrospinal fluid.

Issue Release: 2023

Protease-Sensitive and -Resistant Forms of Human and Murine Alpha-Synucleins in Distinct Brain Regions of Transgenic Mice (M83) Expressing the Human Mutated A53T Protein.

Issue Release: 2023

V180I genetic Creutzfeldt-Jakob disease: Severe degeneration of the inferior olivary nucleus in an autopsied patient with identification of the M2T prion strain.

Issue Release: 2023

Kinetics of Abnormal Prion Protein in Blood of Transgenic Mice Experimentally Infected by Multiple Routes with the Agent of Variant Creutzfeldt-Jakob Disease.

Issue Release: 2023

Movement of Chronic Wasting Disease Prions in Prairie, Boreal and Alpine Soils.

Issue Release: 2023

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