OCT (Optical Coherence Tomography) - Histology

What is Optical Coherence Tomography (OCT)?

Optical Coherence Tomography (OCT) is a non-invasive imaging technique that captures high-resolution cross-sectional images of biological tissues. By using the coherence properties of light, OCT can provide detailed images that are essential for examining the microstructure of tissues. This makes it a valuable tool in the field of Histology.

How Does OCT Work?

OCT works on the principle of interferometry, where light waves are combined to measure differences in path length. A low-coherence light source is split into two beams: one directed at the sample and the other at a reference mirror. The reflected light from both paths is recombined to create an interference pattern, which is then used to generate detailed images of the tissue.

Applications of OCT in Histology

OCT has a wide range of applications in histology, including the examination of tissue morphology, disease diagnosis, and monitoring of treatment efficacy. Its ability to provide real-time, high-resolution images makes it particularly useful in the study of ocular tissues, dermatology, and oncology.

Advantages of OCT in Histological Studies

One of the main advantages of OCT is its non-invasive nature, allowing for the examination of tissues without the need for biopsy or sectioning. Additionally, OCT provides high-resolution images that can reveal microstructural details not visible with conventional imaging methods. This makes it an invaluable tool for researchers and clinicians alike.

Limitations of OCT

Despite its many advantages, OCT does have some limitations. For instance, it has a limited penetration depth, making it less effective for imaging deeper tissues. Furthermore, the quality of the images can be affected by factors such as motion artifacts and optical scattering within the tissue.

Future Directions

Advances in OCT technology are continually being made, with research focusing on improving image resolution, increasing penetration depth, and developing new applications. Innovations such as swept-source OCT and adaptive optics hold promise for expanding the capabilities of OCT in histology and other fields.

Relevant Publications

Discrimination of multiple sclerosis using scanning laser ophthalmoscopy images with autoencoder-based feature extraction.

Issue Release: 2024

Optic Disc Cupping in Neuromyelitis Optica Spectrum Disorder, Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease, and Multiple Sclerosis and Its Relationship With Optical Coherence Tomography Parameters: A Multicenter Study.

Issue Release: 2024

Assessment of retinal atrophy in mixed breed dogs using spectral domain optical coherence tomography (SD-OCT) and electroretinography.

Issue Release: 2024

A Hybrid Model for the Detection of Retinal Disorders Using Artificial Intelligence Techniques.

Issue Release: 2024

Pachy-Reticular Pseudodrusen.

Issue Release: 2024

Anterior segment optical coherence tomography (AS-OCT) in strabismus following trauma.

Issue Release: 2024

Quantitative multimodal imaging characterization of intraretinal cysts vs degenerative pseudocysts in neovascular age-related macular degeneration.

Issue Release: 2024

Optical coherence tomography biomarkers in MYO7A-inherited retinal dystrophy: longitudinal study in pediatric patients.

Issue Release: 2024

Vascular feature identification in actinic keratosis grades I-III using dynamic optical coherence tomography with automated, quantitative analysis.

Issue Release: 2024

Light-evoked deformations in rod photoreceptors, pigment epithelium and subretinal space revealed by prolonged and multilayered optoretinography.

Issue Release: 2024

The effect of temperature on fouling in anaerobic membrane bioreactor: SMP- and EPS-membrane interactions.

Issue Release: 2024

Correlation of limited-early-response status with 12-month CST, BVA, and machine learning-quantified retinal fluid in diabetic macular oedema in routine clinical practice.

Issue Release: 2024

Mechanism of Stent Failure in Patients with Eruptive Calcified Nodule Treated with Rotational Atherectomy.

Issue Release: 2024

An AS-OCT image dataset for deep learning-enabled segmentation and 3D reconstruction for keratitis.

Issue Release: 2024

Evolution of retinal degeneration and prediction of disease activity in relapsing and progressive multiple sclerosis.

Issue Release: 2024

Exploration on OCT biomarker candidate related to macular edema caused by diabetic retinopathy and retinal vein occlusion in SD-OCT images.

Issue Release: 2024

Associations of circulating vitamins with 10-year retinal neurodegeneration: the Alienor Study.

Issue Release: 2024

Pre-Clinical Studies of a Novel Bispecific Fusion Protein Targeting C3b and VEGF in Neovascular and Nonexudative AMD Models.

Issue Release: 2024

Retinal structural thicknesses reflect clinically relevant microstructural white matter abnormalities in neuromyelitis optica spectrum disorders.

Issue Release: 2024

Total variation regularized tensor ring decomposition for OCT image denoising and super-resolution.

Issue Release: 2024

How to Dispose of Glass Slides and Coverslips?

What is Z Line Streaming?

What Happens When Cell Proliferation Goes Awry?

How to Minimize Experimental Errors?

What is a Sharps Container?

How Do Limitations Affect Data Interpretation?

How Does Folic Acid Deficiency Affect Red Blood Cells?

What are the Regulatory Mechanisms of Katanin?

How are lymphomas identified histologically?

What are the Applications of Micropropagation?

Partnered Content Networks

Relevant Topics