What is Instrument Calibration?
Instrument calibration is the process of configuring an instrument to provide a result for a sample within an acceptable range. Calibration checks the accuracy of the instrument by comparing its output with a known standard and making necessary adjustments to ensure precision and reliability.
Before initial use
At regular intervals as recommended by the manufacturer
After any major repairs or replacements
When there is a significant change in environmental conditions
If there is a suspicion that the instrument is not performing correctly
Setting up the instrument in a controlled environment
Using
calibration standards with known properties
Measuring the response of the instrument to these standards
Comparing the instrument's readings with the known values
Adjusting the instrument to align with the standard values
Documenting the calibration results and any adjustments made
Inaccurate diagnosis due to incorrect measurements
Inconsistent results in repeated tests
Compromised patient safety
Increased costs due to repeated tests and instrument downtime
Loss of credibility and trust in the laboratory
Who Is Responsible for Calibration?
Calibration is generally the responsibility of laboratory personnel trained in the use and maintenance of the instruments. However, some laboratories may employ specialized calibration technicians. It is important to follow
laboratory protocols and manufacturer guidelines to ensure proper calibration.
Documentation and Record-Keeping
Documenting the calibration process is crucial for quality control and regulatory compliance. Records should include: Date and time of calibration
Instrument details
Calibration standards used
Results before and after calibration
Any adjustments made
Personnel involved in the calibration
Proper record-keeping ensures traceability and can be invaluable during audits or when troubleshooting issues.
Conclusion
Instrument calibration in histology is essential for ensuring accurate, reliable, and consistent results. By understanding the importance, frequency, and process of calibration, histology laboratories can maintain high standards and provide precise diagnostic information, ultimately contributing to better patient care.
