Focal Adhesion Kinase (fak) - Histology

Relevant Publications

FAK inhibitors in cancer, a patent review - an update on progress.

Issue Release: 2024

A reanalysis and integration of transcriptomics and proteomics datasets unveil novel drug targets for Mekong schistosomiasis.

Issue Release: 2024

A novel FAK-degrading PROTAC molecule exhibited both anti-tumor activities and efficient MDR reversal effects.

Issue Release: 2024

Injectable hybrid hydrogels enable enhanced combination chemotherapy and roused anti-tumor immunity in the synergistic treatment of pancreatic ductal adenocarcinoma.

Issue Release: 2024

Targeted delivery of FAK siRNA by engineered exosomes to reverse cetuximab resistance via activating paraptosis in colon cancer.

Issue Release: 2024

Expression of the αVβ3 integrin affects prostate cancer sEV cargo and density and promotes sEV pro-tumorigenic activity in vivo through a GPI-anchored receptor, NgR2.

Issue Release: 2024

Targeting focal adhesion kinase (FAK) for cancer therapy: FAK inhibitors, FAK-based dual-target inhibitors and PROTAC degraders.

Issue Release: 2024

T-plastin contributes to epithelial-mesenchymal transition in human lung cancer cells through FAK/AKT/Slug axis signaling pathway.

Issue Release: 2024

Focal Adhesion\'s Role in Cardiomyocytes Function: From Cardiomyogenesis to Mechanotransduction.

Issue Release: 2024

IGFBP2 induces podocyte apoptosis promoted by mitochondrial damage via integrin α5/FAK in diabetic kidney disease.

Issue Release: 2024

Pharmacological Blockade of the Adenosine A Receptor Is Protective of Proteinuria in Diabetic Rats, through Affecting Focal Adhesion Kinase Activation and the Adhesion Dynamics of Podocytes.

Issue Release: 2024

Inhibition of Integrin-Associated Kinases FAK and ILK on the In Vitro Model of Skin Wound Healing.

Issue Release: 2024

Adhesion, metastasis, and inhibition of cancer cells: a comprehensive review.

Issue Release: 2024

FAK and p130Cas modulate stiffness-mediated early transcription and cellular metabolism.

Issue Release: 2024

Vinorelbine Improves the Efficacy of Sorafenib against Hepatocellular Carcinoma: A Promising Therapeutic Approach.

Issue Release: 2024

ICAM-1 deletion using CRISPR/Cas9 protects the brain from traumatic brain injury-induced inflammatory leukocyte adhesion and transmigration cascades by attenuating the paxillin/FAK-dependent Rho GTPase pathway.

Issue Release: 2024

Discovery of 2,4-diarylaminopyrimidine derivatives bearing sulfonamide moiety as novel FAK inhibitors.

Issue Release: 2024

Degradation of FAK-targeting by proteolytic targeting chimera technology to inhibit the metastasis of hepatocellular carcinoma.

Issue Release: 2024

Appraisal of folate functionalized bosutinib cubosomes against hepatic cancer cells: In-vitro, In-silico, and in-vivo pharmacokinetic study.

Issue Release: 2024

Knockdown of ribosome RNA processing protein 15 suppresses migration of hepatocellular carcinoma through inhibiting PATZ1-associated LAMC2/FAK pathway.

Issue Release: 2024

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Focal Adhesion Kinase (fak) - Histology

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